Lesson #6:

Mutation

Learning Intention:

I can explain how mutations in DNA, including insertions, deletions, and substitutions, affect protein synthesis and the resulting traits of organisms. 

Success Criteria:

I am successful when I can...


1.  Define mutations and identify the three types: insertion, deletion, and substitution.


2.Describe how each type of mutation (insertion, deletion, substitution) affects DNA sequences.


3.Explain how insertions and deletions typically cause more significant changes to proteins compared to substitutions.


4.Predict possible outcomes of mutations on the structure and function of proteins, using examples.


5.Analyze given DNA sequences and identify specific types of mutations.

Agenda:

Part 1: Warm-Up

Part 2: Vocabulary 

Part 3: Differences Between DNA and RNA

Part 4: Video

Part 5: Codon Chart

Reminders:

1) Test on Thursday, April 10th on all of Genetics

2) Practice Regents #3 due April 21st. 

Standard: 

HS-LS3-2:

"Make and defend a claim based on evidence that inheritable genetic variations may result from (1) new genetic combinations through meiosis, (2) viable errors occurring during replication, and/or (3) mutations caused by environmental factors." 

Part 1:

Protein Synthesis Review

Directions: 

In your notebooks, complete both missing parts of problem 1 and problem 2. 

Example

DNA: TAC CAG GTA ACT

RNA: AUG GUC CAU UGA

Amino Acid: MET+VAL+HIS+STOP

Problem 1

DNA: ?

RNA: AUG UUC GCA UGA

Amino Acid: ?

Problem 2

DNA:TAC GGC GTT AGA

RNA: ?

Amino Acid: ?

Part 2: 

Slow-Reveal 

Warm-Up

(5 min)

Slow Reveal graph - genetics quiz

Part 3: 

THREE BOX INDUCTION

Mutations

(5 min) 

3 box induction mutation

Part 4: 

Text to Text

Text to Self

Text to World 

(5 min)

Mutations Reading

Part 4: 

Echo Echo

Choral Choral

Take-Away

(5 min)

Mutation: Change in the genetic code. 

Types of mutations:

      1) Deletion - A base is removed.

2) Substitution - A base has changed. 

3) Insertion - An extra base has been added

*Mutations that occur in gametes can be passed to offspring (sexual reproduction). If mutations occur in body cells they will pass on to more body cells during mitosis*

Radiation / UV Rays / Chemicals can cause mutations which can lead to cancer. 

Part 5: 

Exit Ticket

(10 min)